Ji-Hye Jun
Asan Medical Center, South Korea
Title: Anemia after gastrectomy in long-term survivors of gastric cancer: A retrospective cohort study
Biography
Biography: Ji-Hye Jun
Abstract
Introduction: The prevalence of gastric cancer in Korea is increasing, and anemia is one of the most common complications of a gastrectomy. The purpose of this study was to estimate the incidence of
anemia and assess its associated factors in long-term gastric cancer survivors.
Methods: This study was a retrospective cohort study of gastric cancer patients who visited a single
medical center from January 2009 to December 2014 in Korea. We included 385 patients who survived
for at least five years after gastrectomy with no recurrence or metastasis. Anemia was defined by World
Health Organization criteria (Hb < 12 g/dL in women and <13 g/dL in men).
Results: Hemoglobin levels decreased from 14.24 ± 1.23 mg/dL before surgery to 13.60 ± 1.57 mg/dL one year after surgery (P < 0.001). The cumulative incidence rate of anemia after surgery increased linearly from 18.7% in the first year to 39.5% in the fifth year. The risk of anemia was higher in females (RR, 2.00; 95% CI, 1.26e3.18), patients that received total gastrectomy (RR, 3.00; 95% CI, 2.09e4.30) and patient with diabetes (RR, 1.87; 95% CI, 1.05e3.22). A higher postoperative BMI decreased the risk of anemia (RR, 0.38; 95% CI, 0.22e0.67).
Conclusions: During five years of follow-up after gastrectomy, the incidence of anemia steadily increased, and the risk of anemia was higher in females, total gastrectomy patients, patients with diabetes, low BMI patients.